... advantage ofthe wisdom ofthe whole team The new-generation, Web-based tools give team members an easy way to contribute to the common repository of tasks and plans These tools unleash the power of ... project plans On the other hand, they increase the cost of errors in the initial design ofthe information hierarchy The whole process becomes very tricky and requires a lot of up-front thinking, ... productivity and therefore curtailing the efficiency ofthe rest ofthe project team The new wave of project management tools puts an emphasis on collaboration and makes teams much more productive These...
... representative ofthe totality ofthe single-stranded overhang, and which may be important for these ligands being able to differentiate telomeric quadruplexes from others in the genome It has ... [19] because it ensures that the 3¢-end is inaccessible to hybridize with the telomerase RNA template, the essential first step in the catalytic cycle The induction of quadruplex stabilization ... when the telomeric protein TRF2 is knocked out This response is a consequence ofthe displacement of bound proteins from the singlestranded overhang, chiefly hPOT1, as well as possible uncapping of...
... most cases the end user isn’t given the option of buying separately the transmission link from their home or office to the switch Rather, they have to buy that portion ofthe link as part of a bundled ... ISPs and then treating all ISPs the same with respect to the unregulated nature ofthe information service component, regardless of whether or not the ISP was owned by the owner ofthe underlying ... time to time, had members ofthe Commission up here to discuss these matters and to inquire of them how they could interpret the statute in the curious way in which they have, but we find ourselves...
... preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe ... for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the ... for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the preparation ofthe SPCR Phase Funding for the...
... assess the pharmaceutical industry on the basis ofthe number of jobs and the volume of salaries generated domestically, investors on the basis of future profits, and consumers on the basis of variety, ... NOTICE: The project that is the subject of this report was approved by the Governing Board ofthe National Research Council, whose members are drawn from the Councils ofthe National Academy of Sciences, ... of research Determination ofthe specific relative importance of each factor is beyond the scope of this study The basic conclusion to be drawn, however, remains that the overall balance of several...
... expression ofthe partial heat capacity ofthe protein relative to the heat capacity ofthe protein in the native state the monomerization ofthe dimer), and the latter process precludes the study ofthe ... residues of one subunit and Arg104 residues ofthe other [8] In this dimer, the relative positions ofthe two subunits would prepare the molecule for the swapping ofthe N-terminal domain while, in the ... nearly 100% ofthe dimer was interchanging the N-terminal moiety This result is in agreement with the fact that in the Fig Assessment ofthe degree of swapping ofthe N-terminal domain in PM8E103C...
... president ofthe University of Michigan and a member ofthe U.S Secretary of Education’s Commission on the Future of Higher Education, echoed the sentiments of many when he noted that the decision ... Cheryl Hill of Hampden-Sydney College for their assistance in obtaining other data used to prepare this report Current members ofthe AAUP’s Committee on the Economic Statusofthe Profession also ... percent ofthe average salary of assistant professors at the ninetyfifth percentile The fact that assistant professors are more mobile than their senior colleagues may partly explain the smaller...
... mutant to the wild-type phenotype [32] Therefore, the function ofthe PAS domains of these proteins in quinone sensing remains obscure It is interesting to note that the PAS domainofthe phosphorelay ... the presence of a PAS domain was recently predicted in front ofthe transmitter domainofthe BvgS protein [13] Similarly, the EvgS protein contains a sequence with characteristics of a PAS domain ... Effects of mutations in the BvgS PAS domain on quinone sensing The negative effect on autophosphorylation observed after addition ofthe oxidized ubiquinone to the histidine kinases may either be the...
... lipofectin reagent (Gibco BRL) · 106 cells were transfected with lg ofthe reporter plasmid pCAPCAT, and either 0.5 lg of each ofthe clones ofthe overlapping AcMNPV k library or 1.0 lg of each ... interaction would support the contention that IE1 targets thereplication machinery to the origin of DNA replication Such an arrangement in the formation ofthe preinitiation replication complex has ... Fig Model ofthe AcMNPV replication complex Long arrows point in the direction of DNA synthesis The model is based on the accumulation of LEF interaction data presented in this and other publications,...
... Proposed Model for theReplicationof Parvovirus LuIII Proposed Model for theReplicationof Parvovirus LuIII A model for thereplicationofthe (+) and the (-) strand of LuIII is shown The NS1 nick ... hairpin, capable of acting as an origin of replication, lacks the arrangement ofthe specific domains present in the dimer duplex intermediate of MVM, the only active form ofthe left hairpin ... for thereplicationof LuIII Lt-Lt Parvovirus DNA replication starts when the 3' hydroxyl group at the left end ofthe viral genome primes the synthesis of a complementary strand, leading the formation...
... Proposed Model for theReplicationof Parvovirus LuIII Proposed Model for theReplicationof Parvovirus LuIII A model for thereplicationofthe (+) and the (-) strand of LuIII is shown The NS1 nick ... hairpin, capable of acting as an origin of replication, lacks the arrangement ofthe specific domains present in the dimer duplex intermediate of MVM, the only active form ofthe left hairpin ... for thereplicationof LuIII Lt-Lt Parvovirus DNA replication starts when the 3' hydroxyl group at the left end ofthe viral genome primes the synthesis of a complementary strand, leading the formation...
... in the same distance (about m) from the stem of five selected trees The cylinder ofthe soil probe used for this purpose had the inner diameter of cm and the height (depth of space sampled) of ... created in the programme Microsoft Excel For further processing of data, various modules of Statistica 6.0 (StatSoft Inc.) were used The correlation was tested at the levels of significance of 0.05, ... and in the first half ofthe 1980s the health conditions of stands gradually worsened In the period after 1988 health improvement and decline ofthe stands alternated in individual years In the...
... evaluate the closeness ofthe nutrient statusofthe spruce stands and to assess the closeness of chemical properties ofthe studied sites The results were tested by PCA To test the homogeneity of ... models ofthe soil system data MATERIAL AND METHODS Theory about site survey The Hrubý Jeseník Mts are an important geotectonic unit ofthe northeastern part ofthe Bohemian Massif (in the direction ... (podzolization) and on the basis of different impacts of management The currently minimized level of air-pollution load in the whole area is an important aspect of ecology of these plots It is a...
... lane 2) The degree of Bcl-2 expression in the early stage of EAE (G1, day PI) (Fig 1, lanes and 4) was the same as in the Pe a k Re c o ve ry Bc l-2 Fig A representative photograph of Western ... Furthermore, the lack of apoptosis in perivascular cuffing in EAE is caused by the generation of superoxide in invading macrophages, at least in part [4] Our results suggest that the apoptosis of ... summarizes the expression of Bcl-2 by cell phenotype The intensity of Bcl-2 staining in neurons in EAE was weaker than in neurons in the normal and CFAimmunized groups It suggests that the decreased...
... standard error ofthe species mean The grey lines represent the upper and lower confidence interval limits (95%) ofthe relationship between ∆ and WUE The Symbols correspond to the successional ... the y-intercept ofthe theoretical line (–0.095 and 27.00, respectively) fell in the confidence interval (95%) ofthe slope (−0.084 ± 0.024) and the y-intercept (26.87 ± 1.56) ofthe relationship ... between ∆ and WUE There was a strong positive and linear relationship between ∆ of sunlit leaves of dominant canopy trees and the leaves of potted seedlings ofthe same species grown in the glasshouse...
... when evaluating the performance ofthe 1994/1995 stock Discussion There are two main aspects to the results ofthe study First, information is provided on the physiological statusof Douglas fir ... showed that the shoot system had a clear annual cycle of dormancy development However, the roots ofthe seedlings were mitotically highly active throughout the winter in the first years of observation ... recorded at the end ofthe first growing season of each year only Because there was some variation in initial planting stock size, the height increment data were analysed as percentage of initial...
... information about: (1) the mental statusof heroin addicts who apply for treatment of their opiate addiction, and (2) The degree of association of their baseline mental status with age, sex, substance ... scores were then standardised as z-scores to facilitate the comparisons of scores among the factorial measures All the subjects were then grouped into different subtypes on the basis ofthe highest ... investigated on the basis ofthe DSM-IV decision trees for differential diagnosis Each decision tree starts with a set of clinical features When one of these features is a prominent part ofthe presenting...
... samples from the harvest to the time ofthe experiment must be monitored carefully Often, the temperature ofthe samples and the time period that elapses until the researcher receives the sample ... percentage ofthe peripheral blood cells, has been challenging because ofthe large number of cells needed for biochemical assessment of signaling status and the relatively poor efficiency of transfection ... in the kinase itself or an upstream kinase [7,10] Another approach is to demonstrate reversibility of staining in the presence ofthe immunogen peptide as shown in Fig or in the presence of a...
... vivo in the presence of BAFF blockade [26] BAFF and APRIL enhance the survival of plasmablasts, but there are still conflicting data about whether they are required for the survival of long-lived ... and because of possible alterations in the strength ofthe BCR signal, but the repertoire of established memory cells is unlikely to be altered Fourth, depletion of B cells by blockade of BAFF should ... [12,16] To further complicate matters, APRIL and BAFF can form heterotrimers [17] and the extracellular domainof APRIL can form a hybrid molecule with the intracellular domainof TWEAK (TWE-PRIL;...
... 7:9 ment of food allergy The prevalence ofthe transgenic protein in food and its resistance to processing and cooking may affect the amount of protein ingested, and the resistance ofthe protein ... amino acids in length, the amino-acid length ofthe shorter member of each protein pair was compared with the length of a typical full-length protein isoform to determine if the FARRP entry was ... database that meet the indicated identity criterion Inset shows a further breakdown in the number of pairs meeting only the 8-mer criteria where the amino acid length of both proteins in the pair is...